The Reality of 7 Oh Kratom Withdrawals

Kratom is derived from the plant Mitragyna speciosa and contains several bioactive alkaloids, with mitragynine and 7-hydroxymitragynine (7-OH) being the most studied.

7-Oh kratom is a fairly new product, one that enhances the traditional kratom that many people are familiar with, leading to increased dependency and increased risks for your overall health, especially with chronic use. The addictive potential of 7-OH is significant due to its high potency and strong binding to opioid receptors, raising concerns about dependence and abuse.

We will get straight to the point: what should you expect from 7 Oh kratom withdrawals if you have to go through this difficult process?

The primary kratom alkaloid, mitragynine, is much more concentrated in 7-Oh kratom. 7-hydroxymitragynine (7-OH) is a potent metabolite of mitragynine and is reported to be up to 13 times more potent than morphine in some lab models. This means that it is likely to have stronger impacts on the central nervous system with effects that mimic opioid use.

In short, the kratom alkaloids act similarly to illicit and prescription opiate drugs. Withdrawal effects include tremors, digestive system upset, insomnia, sweating, anger, and depression.

The reason that withdrawal symptoms are so much stronger for 7-Oh kratom is due to the chemical makeup of the substance. This form of kratom is a much stronger concentration of traditional kratom, which has a serious impact on your overall health and the risks associated with taking it.

Kratom’s major alkaloids, the mitragynine and 7-hydroxymitragynine, are both found in the plant where the substance originates. Mitragynine is the predominant alkaloid in kratom, making up about 60-65% of the alkaloids present, and plays a significant role in kratom’s effects, including its contribution to dependence and withdrawal potential.

The Mitragyna speciosa kratom plant, native to Southeast Asia, acts as a partial agonist on the brain’s opioid receptors.

Kratom’s effects are dose-dependent and include stimulant, analgesic, and sedative properties, which can result in pain relief for the user alongside mood and anxiety benefits. Both of these can reinforce the effects that keep you taking the substance again and again. 7-Oh kratom use has raised concerns due to its similarities to opioid use disorder. Kratom has seen an increase in abuse in recent years. However, understanding that there is more than one form of kratom is essential.

Here is what you can expect when looking at the difference between typical kratom alkaloids and 7-Oh kratom.

7-Oh kratom isn’t as well-known or recognized as traditional kratom, which has been around for quite some time. Unfortunately, there aren’t any clear guidelines on what exactly goes into the substance. Some people think that 7-Oh is a nod to the fact that the exact products are in a 70:1 ratio or that the effects last much longer.

Regardless of the specifics, one thing is clear: it contains high doses of both its mitragynine and 7-Hydroxymitragynine. The total alkaloid content of kratom acts on the central nervous system by activating the same receptors in the brain as other drugs with addictive potential. Because of the varying concentration levels, it can be harder to dose and poses a greater risk of developing an addiction to its properties.

Compulsive use, which refers to persistent use despite harm, is a key aspect of behavioral addiction and should be distinguished from dependence. Dependence refers to both physical and psychological adaptation, which can result in withdrawal symptoms when kratom use is stopped.

This use of kratom extracts might have some therapeutic potential, but it’s important to balance the risks. High potency kratom leaves and extract products pose public health risks, especially when there is no monitoring in place. Kratom is not controlled under the Controlled Substances Act in the United States, but some states have regulations against its possession and use.

Of course, the real reason why so many people turn to 7-Oh kratom is that it’s advertised as having more of the positive effects that people love about the traditional kratom.

Most sellers will tell you that it lasts longer and has those sedative properties that are often reserved for opioids, but without mentioning the very real risks of drug abuse and addiction.

The problem is that it also acts on the brain’s opioid receptors and can result in dependence, similar to other opiates. However, evidence suggests its abuse potential is limited when used responsibly. However, kratom misuse can lead to adverse effects, dependence, and withdrawal symptoms. If you find that you have a hard time functioning without kratom in your day-to-day life, it may be time to consider detox for your withdrawal symptoms.

Kratom products are commonly found in gas stations, smoke shops, and online vendors, despite the lack of FDA approval.

Unfortunately, kratom isn’t a controlled substance that the Food and Drug Administration monitors. It also isn’t included in the Controlled Substances Act. But that doesn’t mean there aren’t real effects when you try to stop using it for good.

In many people, the withdrawal signs are very similar to those seen with opioid withdrawal because kratom acts on the same mu opioid receptor in the brain. While kratom dependence can develop, it is generally considered less severe than opioid dependence. You can’t get opioid-like effects without running some of the risk of drug dependence and withdrawal seen with 7-Oh kratom.

Withdrawal signs with these “opioids” can include:

• Jerky movements of the arms and legs or tremors
• Insomnia
• Depressed appetite, nausea, vomiting, or diarrhea
• Abdominal pain
• Watery eyes
• Runny nose
• Hot flashes and profuse sweating
• Restlessness
• Anger, depression, or irritability

Kratom withdrawal symptoms generally appear within 12 to 48 hours of stopping use and can last about a week, though psychological effects may persist longer. The severity of kratom withdrawal symptoms is generally milder compared to traditional opioid withdrawal, but can still be significant for many users. Symptoms may be more subtle at lower doses of kratom, while higher doses and concentrated forms of the drug, like kratom shots, can increase the risk and intensity of withdrawal.

Compared to those with opioid tolerance, it was generally held that kratom users often experience less severe withdrawal, but the experience can still be challenging. And when it comes to the 7 Oh kratom withdrawal timeline and symptoms, it can be quite similar to heroin or fentanyl, with past clients reporting even more difficulty (particularly in terms of depression during detox) than with traditional, illicit opioid drugs.

It’s also worth noting that you’ll likely experience cravings for more 7-Oh kratom as it works its way out of your system. It may be some time before these cravings let up, which is why it can be crucial to get into a detox program for kratom.

One thing to be aware of is that your likelihood of experiencing more serious side effects can depend largely on what else you were using with the psychoactive botanical kratom. It’s very common to find that someone who has taken 7-Oh kratom is also taking other drugs and alcohol, or other substances, which should be considered during detoxification and treatment to prevent drug interactions and ensure safety.

Not only does this make detox more difficult, but it also runs the risk of greater withdrawal effects.

When you mix 7-Oh kratom alkaloids with illicit drugs, alcohol, or other substances, you can develop a physical dependence on the combination of substances. There is also a risk of serious adverse events, including liver toxicity, seizures, and even death. This has been confirmed in recent reports of 7 oh kratom overdose in the Los Angeles area.

Liver toxicity is a particular risk associated with kratom, especially products with high levels of 7-OH. Additionally, neonatal abstinence syndrome can occur in newborns exposed to kratom in utero. You might also develop respiratory depression, liver issues, or serious conditions that can lead to death if untreated.

Like classical opioids, 7-Oh kratom withdrawal symptoms tend to surface fairly quickly following your last dose. Most people experience the first symptoms around twelve to twenty-four hours after their final dose of kratom use. If they’ve developed physical dependence due to extended or heavy use, the effects could last for a few days.

Most people feel a bit better once the active compounds leave their system in the first three days.

However, this does depend on the medicinal chemistry of the kratom you were using, your degree and frequency of use, your unique body chemistry, and whether you have a history of prior opioid use. People with prior opioid use may experience more severe withdrawal symptoms. Some people will require about a week of recovery before the worst of the withdrawal symptoms from this dietary ingredient are over.

Withdrawal symptoms are often assessed using standardized instruments such as the clinical opiate withdrawal scale (COWS), which helps clinicians evaluate the presence and severity of withdrawal signs. Clonidine is used off-label to help manage symptoms of opioid withdrawal and has also been seen to be beneficial for kratom withdrawal.

As noted above, treating major depression that can arise during withdrawal from 7 Oh products is often helpful, with many clients reporting this is what helped them to stay clean rather than relapse during the difficulties of detox.

The Risks of Cold Turkey Withdrawal from 7 Oh Kratom

To help ease the withdrawal symptoms of 7 Oh kratom, South Shores Detox can help you with medication-assisted treatments (MAT), which may include medications like buprenorphine or clonidine to ease withdrawal symptoms.

Our medical team is well-versed in clinical pharmacology and can offer you a range of prescriptions that will target your exact needs without creating dependence. Plus, you’ll be supervised while taking them to ensure that there are no reactions or adverse side effects. When considering co-occurring mental disorders, our approach also includes assessment and support for psychiatric conditions alongside substance use.

We follow guidelines informed by the Diagnostic and Statistical Manual (DSM-5) for substance use and related disorders, even though kratom use disorder is not specifically listed. Our treatment is supported by current research, including the most recent studies by the National Institute on Drug Abuse (NIDA), to ensure evidence-based care.